Spasticity is a condition in which certain
muscles are continuously contracted. The constant muscle contraction causes
stiffness or tightness of the muscles and can interfere with normal movement,
speech and gait in a patient.
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Detailed Report Summary:
Spasticity
is usually caused by damage to the portion of the brain or spinal cord that
controls voluntary movement. This damage causes a change in the balance of
signals between the nervous system and muscles, leading to increased activity
in muscles.
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Spasticity
negatively affects muscles and joints of the extremities and is particularly
harmful to growing children. Currently available treatment options for this
disease include oral medications and interventional procedures. Certain
conditions that may cause spasticity are traumatic brain injury, spinal cord
injury, brain damage due to a lack of oxygen, stroke, encephalitis, and
meningitis.
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The drug
candidates of for treating this condition include, but are not limited to,
Arbaclofen extended release and Botulinum toxin E. Some of the companies having
drugs in spasticity pipeline are Osmotica Pharmaceutical, Ipsen Pharma, and
Canbex Therapeutics Ltd.
The report
provides a comprehensive understanding of the pipeline activities covering all
drug candidates under various stages of development, with the detailed analysis
of pipeline and clinical trials.
Pipeline
analysis of drugs by phases includes product description and development
activities including information about clinical results, designations,
collaborations, licensing, grants, technology, and others.
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