Hyperoxaluria Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations

Hyperoxaluria is a medical condition which involves increased oxalate in urine. The causes of hyperoxaluria include consumption of oxalate-rich foods, intestinal disorders and genetic disorders. The disease is categorized into different types which includes primary hyperoxaluria,...

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Human Immunodeficiency Virus (HIV) Fusion Inhibitors Therapeutics - Pipeline Analysis, Clinical Trials & Results

Human immunodeficiency virus (HIV) fusion inhibitors is the new class of antiretroviral drugs for the treatment of HIV infections. Failure of combination antiretroviral therapy in patients with HIV, has increased the risk of disease progression. This has led to the development...

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Tau Protein Inhibitors Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations

Tau protein is found in abundance in neurons of the central nervous system. This protein is a product of microtubule-associated protein tau (MAPT) gene, that is located on chromosome 17. It is associated with pathologies of several nervous system disorders, such as dementia,...

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Prader-Willi Syndrome – Epidemiology Insights

Prader-Willi syndrome (PWS) is a complicated genetic condition which can affect various parts of the body. During infancy, this condition is identified by weak muscle tone (hypotonia), problems in feeding, poor growth, and delay in development. Request to Get the Sample...

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Glaucoma – Epidemiology Insights

Glaucoma can be described as a group of diseases characterized by cupping of the optic nerve head and visual-field damage. These diseases differ from each other in terms of their causes, risk factors, demographics, symptoms, duration, treatment, and prognosis. Report Description: https://www.pharmaproff.com/report/glaucoma-epidemiology-forecast The...

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Hyperkalemia Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations, Collaborations

Hyperkalemia is referred to as increased levels of potassium in blood which results in cardiac arrest and death. Potassium levels above 5.1 mEq/l are considered as the hyperkalemia condition. The main causes of hyperkalemia are potassium sifting out of cells into the blood...

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Wiskott-Aldrich Syndrome Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations

Wiskott-Aldrich syndrome is a hereditary immunodeficiency disorder characterized by abnormal functioning of immune system and decreased ability to form blood clots. The abnormality in the platelets leads to easy bruising effects in case of prolonged bleeding. The white blood...

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Vaginitis Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations, Collaborations

Vaginitis refers to the inflammation of vagina. It affects women of all ages but is most common during the reproductive years. Vaginitis occurs due to change in the balance of the yeast and bacteria that normally live in the vagina. Access Detailed Report Summary: https://www.pharmaproff.com/report/vaginitis-therapeutics-pipeline-analysis This...

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Uterine Fibroids Therapeutics - Pipeline Analysis , Clinical Trials & Results

Uterine fibroids, also known as leiomyomas or myomas, are non-cancerous growths that develop from the muscle tissue of the uterus. The size, shape, and location of fibroids can vary greatly. They may be present inside the uterus on its outer surface, or within its wall, or...

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Turner Syndrome Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations

Turner syndrome is a chromosomal condition, which occurs when one of the two X chromosomes normally found in women is missing or incomplete. The disease alters the growth and development in females. The symptoms can vary among women who have Turner syndrome. Women with this...

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Reperfusion Injury Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations

Reperfusion injury is the damage to tissues caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen (anoxia, hypoxia). It influences the patient’s outcome after myocardial infarction, stroke, cardiovascular surgery, and organ transplantation. Access Detailed...

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Post-Operative Nausea and Vomiting Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations

Post-operative nausea and vomiting is one of the complications of anaesthesia given to the patients at the time of a surgery. The state of having unpleasant sensation subjected to desire of vomiting is known as nausea whereas, vomiting is the forceful expulsion contents present...

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Mucopolysaccharidosis III (MPS III) (Sanfilippo Syndrome) Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results

Mucopolysaccharidosis type III (MPS III), also known as Sanfilippo syndrome, is a progressive disorder that primarily affects brain and spinal cord (central nervous system). People with MPS III generally do not display features at birth, but they begin to show signs and symptoms...

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Viral Bronchiolitis Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations

Viral bronchiolitis is an inflammatory disorder which is characterized by obstruction of small airways, necrosis and edema of the epithelial cells, and increased mucus production. The disease is most commonly caused by an infection caused by respiratory syncytial virus. Access Detailed...

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Pleural Effusion Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results

Pleural effusion is the fluid build-up in the pleural space and is categorized into two types which includes exudate and transudate. Transudate is usually composed of ultrafiltrates of plasma due to heart failure or cirrhosis; while, exudate is caused by inflammatory conditions....

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Interstitial Lung Disease Therapeutics - Pipeline Analysis

interstitium of the lungs. The interstitium is a lace like network of the tissue that provide support to the air sacs and the capillaries in the interstitium which allows the gas exchange between the blood and alveolar tissues. Some of the types of the condition include...

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Nav1.7 Voltage-Gated Sodium Channel Inhibitors Therapeutics - Pipeline Analysis

Nav1.7 voltage-gated sodium channel inhibitors are the drug candidates that target the sodium channels Nav1.7 and have been significant in pain management. The sodium channels Nav1.7 receptors are generally found in two types of neurons: nociceptive pain neurons, such as...

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RNA Interference (RNAi) Therapeutics - Pipeline Analysis , Clinical Trials & Results

RNA interference (RNAi) is a molecule type that silences the gene and limits the transcription of the mutated gene. Gene silencing is a novel mechanism that inactivates the transcripts of mutated gene, by activating sequence specific RNA degradation process. The process of...

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Rho Kinase Inhibitor Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations, Collaborations

Rho kinase inhibitor, also known as ROCK inhibitor, inhibits the rho kinases, a family of small GTP-binding protein. Rho kinases are found to regulate cell motility, proliferation, shape, gene expression, apoptosis, and are also involved in the signalling pathway. The inhibition...

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p53 Antigen Modulators Therapeutics - Pipeline Analysis, Clinical Trials & Results, Patents, Designations

p53 is the tumor suppressor transcription factor that activates to various stimulus, including uncontrolled cell proliferation, oncogene over-expression, and DNA damage. p53 antigen modulators helps in preventing cancer development through regulation of cell cycle and apoptosis....

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Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Inhibitor Therapeutics - Pipeline Analysis , Clinical Trials & Results

Cytotoxic T-lymphocyte antigen-4 (CTLA-4) plays important role in the T-cell regulation at an early stage of naive T-cell activation, primarily in the lymph nodes. CTLA-4 has emerged as an attractive cancer immunotherapy as a part of “immune checkpoint blockade”. CTLA-4 pathway...

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Cyclophilin Inhibitors Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations

Cyclophilin befits in the group of protein that shows peptidyl-prolyl cis-trans isomerase activity, found in all types of cells. In humans, 16 cyclophilins have been identified till date. Cyclophilin A, a member of cyclophilin group, mediate the action of immunosuppressive drugs....

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Cell Cycle Inhibitors Therapeutics - Pipeline Analysis , Clinical Trials and Results Report

Cell cycle inhibitors include cyclin inhibitors and cyclin-dependent kinases (CDKs), which plays major role in developing new class of anti-cancer therapies. Also, cell cycle inhibitors in combination with chemotherapy, overcome drug resistance and improve cytotoxic efficacy....

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Androgen Receptor Antagonist Therapeutics - Pipeline Analysis, Clinical Trials & Results

Androgens are responsible for the development of male characteristics by binding to androgen receptors. Androgen receptor plays an important role in the development and progression of prostate cancer. Thus, it has been an attractive target for the clinical interventions and...

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Androgen Receptor Antagonist Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents

Androgens are responsible for the development of male characteristics by binding to androgen receptors. Androgen receptor plays an important role in the development and progression of prostate cancer. Thus, it has been an attractive target for the clinical interventions and treatment...

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Alpha-Synuclein Inhibitor Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations

Alpha-synuclein is a protein that is abundantly found in the brain. The minimal amount of alpha-synuclein is also found in the heart and other tissues. The protein is prominently found at the tips of the nerve cells. It helps in the maintaining supply of the synaptic vesicle...

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Dasatinib - Drug Insight Insights, Potential Business Strategies, Mergers and Acquisitions, Revenue Analysis

Dasatinib (Sprycel) medicines are generally used to treat people with chronic myeloid leukemia and people with acute lymphoblastic leukemia who have been tested positive for the Philadelphia chromosome (Ph+). Developed by Bristol-Myers Squibb Company, Dasatinib has been approved...

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